Pilot study of a commercialized human papillomavirus (HPV) genotyping assay: comparison of HPV risk group to cytology and histology.

نویسندگان

  • Philip E Castle
  • Mark Sadorra
  • Francisco Garcia
  • E Blair Holladay
  • Janet Kornegay
چکیده

We evaluated a commercialized PCR assay, Linear Array, that detects 37 human papillomavirus (HPV) genotypes, using a sample of liquid cytology specimens (n = 534). We found a strong association of an increasing level of HPV risk (HPV type 16 [HPV16] > HPV18 > other carcinogenic types > noncarcinogenic types > negative specimens) with increasing severities of cytologic interpretations (P(Trend) < 0.0005) and histologic diagnoses (P(Trend) < 0.0005).

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 44 11  شماره 

صفحات  -

تاریخ انتشار 2006